Star race car Lightning McQueen and his pal Mater head overseas to compete in the World Grand Prix race. But the road to the championship becomes rocky as Mater gets caught up in an intriguing adventure of his own: international espionage.
- Cast

Owen Wilson
as Lightning McQueen (voice)

Larry the Cable Guy
as Mater (voice)

Michael Caine
as Finn McMissile (voice)

Emily Mortimer
as Holley Shiftwell (voice)

John Turturro
as Francesco Bernoulli (voice)

Eddie Izzard
as Sir Miles Axlerod (voice)

Thomas Kretschmann
as Professor Z (voice)

Joe Mantegna
as Grem (voice)

Peter Jacobson
as Acer (voice)

Bruce Campbell
as Rod "Torque" Redline (voice)

Tony Shalhoub
as Luigi (voice)

Darrell Waltrip
as Darrell Cartrip (voice)

Guido Quaroni
as Guido (voice)

Brent Musburger
as Brent Mustangburger (voice)

Jason Isaacs
as Siddeley / Leland Turbo (voice)

David Hobbs
as David Hobbscap (voice)

Stanley Townsend
as Victor Hugo / Vladimir Trunkov / Ivan the Tow Truck (voice)

Lloyd Sherr
as Fillmore / Combat Ship (voice)

Paul Dooley
as Sarge (voice)

Michel Michelis
as Tomber (voice)

Sig Hansen
as Crabby (voice)

Franco Nero
as Uncle Topolino (voice)

Vanessa Redgrave
as The Queen / Mama Topolino (voice)

Bonnie Hunt
as Sally Carrera (voice)

Cheech Marin
as Ramone (voice)

Jenifer Lewis
as Flo (voice)

Michael Wallis
as Sheriff (voice)

Katherine Helmond
as Lizzie (voice)

John Ratzenberger
as Mack (voice)

Jeff Garlin
as Otis (voice)

Patrick Walker
as Mel Dorado (voice)

Lewis Hamilton
as Lewis Hamilton (voice)

Velibor Topic
as Alexander Hugo (voice)

John Mainieri
as J. Curby Gremlin (voice)

Brad Lewis
as Tubbs Pacer (voice)

Richard Kind
as Van (voice)

Edie McClurg
as Minny (voice)

Teresa Gallagher
as Mater's Computer (voice)

Jeff Gordon
as Jeff Gorvette (voice)

John Lasseter
as Additional Voices (voice)
Mark Winterbottom
as Frosty (voice)

Fernando Alonso
as Fernando Alonso (voice)
Vitaly Petrov
as Vitaly Petrov (voice)
Jan Nilsson
as Flash (voice)
Memo Rojas
as Memo Rojas (voice)
Jacques Villeneuve
as Jacques Villeneuve (voice)

Sebastian Vettel
as Sebastian Vettel (voice)
- See full cast...